- Foltx Tablet contains the following ingredients
Vitamin B12 1mcg
Foltx Tablet contains folate in the form of L-methylfolate which is the biologically active folate isomer, and vitamin B12, which means it works immediately in the body when absorbed. As co-enzymes, the B vitamins are essential components in most major metabolic reactions. They play an important role in energy production, including the metabolism of lipids, carbohydrates, and proteins.
B vitamins are also important for blood cell production, hormone production, nervous system function, normal homocysteine metabolism, and proper methylation. The ingredients of Foltx (Vitamin B12 and folate) are coenzymes in DNA and RNA metabolism. Both of these B vitamins assist in homocysteine metabolism. Folate serves as a methyl donor and B12 as a coenzyme in the conversion of homocysteine to methionine.
How Foltx is metabolized?
The structure, binding, absorption, transport, metabolism, function, and interaction of Foltx (vitamin B12 and folates) and the polymorphisms of folate-related enzymes can be found elsewhere. A key interaction is that between vitamin B12 and folate in the synthesis of methionine from homocysteine by methionine synthase, in which both 5-methyltetrahydrofolate and methyl-vitamin-B12 are cofactors, a reaction that can be inhibited by nitrous oxide.
The folate cycle, which synthesize methyl groups, is essential for many genomic and non-genomic methylation reactions, via S-adenosylmethionine and, indirectly, for the synthesis of purines and thymidine and, therefore, of nucleotides, DNA, and RNA.
Why Take Foltx During Pregnancy / Lactation?
Folate and B12 deficiencies, health consequences:
- Folate Deficiency
There is strong evidence that folate deficiency causes megaloblastic anemia. In regions where folate deficiency is more common during pregnancy and lactation, a few studies have associated megaloblastic anemia with prolonged lactation and multiple pregnancies.
- B12 Deficiency
Vitamin B12 deficiency at the population level increases the prevalence of anemia, either in the elderly or in people consuming low amounts of animal-source foods, in contrast, megaloblastic anemia is common when vitamin B12 deficiency is more severe, such as in clinical cases of pernicious anemia (defined as vitamin B12 deficiency due to malabsorption caused by absence of intrinsic factor) and in some infants exclusively breastfed by mothers who are strict vegetarians.
- Pregnancy outcomes
- Birth defects
- Cognitive function
- Child development
- Neuropathy and sustained spinal cord degeneration.
Foltx Indications and Contraindications
The recommended dosage of Foltx is 1 to 2 tablets daily in the following conditions;
- Disturbances in folate metabolism.
- Folate and Vitamin B12
Foltx is not an antidepressant. However, it may enhance the effects of antidepressant medications. Foltx may be used throughout pregnancy or while you are trying to get pregnant. You should not use Foltx if you have ever had an allergic reaction to l-methylfolate or vitamin B12.