Fybogel sachets is used for symptomatic relief of irritable bowel syndrome. It contains ispaghula husk which is a natural plant material and high in fiber. It works by increasing the bulk of contents of the gut passing through the digestive system.
Mebeverine (the second ingredient of Fybogel Sachets) is an antispasmodic drug which relieves spasm and cramps, which occur in the gut causing pain. The combination is used to relieve the symptoms of irritable bowel syndrome and is effective in relaxing the spasms of the gut, relieving pain. Fybogel Sachets also help restore and maintain bowel regularity.
Ingredients of Fybogel Sachets
Each Fybogel Sachet contains;
- Ispaghula Husk
- Mebeverine HCl
How Fybogel Sachets work?
- Ispaghula Husk
it has a physical mode of action and does not depend upon absorption from the gastrointestinal tract. It is capable of absorbing up to 40 times its own weight of water in vitro and part of its activity can be attributed to its action as a simple bulking agent. In addition, colonic bacteria are believed to use the hydrated material as a metabolic substrate. This results in an increase in the bacterial cell mass with a consequential softening of the feces.
- Mebeverine HCI
it has been shown to be nearly completely absorbed following oral administration, but first-pass metabolism is extensive and plasma levels of unchanged drug are very low. This supports the view that it acts directly on the muscle of the gastrointestinal tract, rather than as a result of systemic absorption.
Mebeverine HCI is a musculotropic antispasmodic agent which exerts a direct action on the smooth muscle of the gastrointestinal tract, relieving the spasm without affecting gut motility.
Dosage and Administration
For adults and children over 12 years of age, the recommended dosage of Fybogel is one sachet in the morning and evening, taken 30 minutes before meals. A 3rd dose may be taken before the midday meal if necessary.
Pour the contents of 1 Fybogel Sachet into a glass of cold water, stir well and drink immediately.
Side Effects of Using Fybogel Sachets
Flatulence and abdominal bloating may be experienced during the first few days of treatment, but should be diminished during continued treatment. Individuals with hypersensitivity to any of the ingredients mentioned above should not use Fybogel Sachets.
When to avoid Fybogel Sachets?
Do not use Fybogel sachets in case of;
Intestinal obstruction, paralytic ileus, fecal impaction and colonic atony such as senile megacolon. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency, allergic to peanut and soya should also not use Fybogel sachets.
Fybogel Sachets during Pregnancy and Lactation
There are no adequate and well-controlled studies in pregnant women. It is therefore, recommended that, care should be taken when using Fybogel during pregnancy and lactation.
What to do in case of Overdose?
In the event of overdose, conservative measures should be taken. The patients may notice abdominal discomfort and flatulence, and attention should be paid to maintaining an adequate fluid intake, particularly if the Fybogel Sachets have been taken without water, contrary to the administration instructions.