Poisoning due to an overdosage of Betaloc Zok may lead to severe hypotension, sinus bradycardia, atrioventricular block, heart failure, cardiogenic shock, cardiac arrest, bronchospasm, impairment of consciousness (or even coma), nausea, vomiting, and cyanosis.
Concomitant ingestion of alcohol, antihypertensive medicines, quinidine, or barbiturates may aggravate signs and symptoms.
The first manifestations of overdosage set in 20 minutes to 2 hours after the drug’s ingestion.
Treatment of Betaloc Zok Overdose
Induction of vomiting or gastric lavage. In the presence of severe hypotension, bradycardia, and impending heart failure, administer a β-stimulator (e.g. prenalterol) intravenously at 2-5 minutes intervals until the desired effect is achieved. Where a β-stimulator is not available, administer Atropine sulphate I.V. in order to block the vagus nerve.
If a satisfactory effect is not achieved, agents such as dopamine, dobutamine, metaraminol or noradrenaline may be administered.
Glucagon in a dose of 1-10 mg can also be administered. Pacemaker may be necessary. To combat bronchospasm, a Beta-stimulant can be given I.V.
Observe that the dosages of antidotes needed are much higher than recommended therapeutic dosages.
Related Links
- Betaloc Zok Side Effects and Drug Interactions
- Contraindications and Drug Warnings
- Use During Pregnancy & Lactation
- Betaloc Zok Over Dosage (must read)
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