• Thrombonil 75 Tablet Contains
    Clopidogrel 75mg

Thrombonil 75 mg Tablets


What is Thrombonil 75 Used For?

Thrombonil is indicated for the reduction of atherothrombotic events as follows:

  • Recent MI, Recent Stroke or Established Peripheral Arterial Disease
    For patients with a history of recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease, Thrombonil has been shown to reduce the rate of a combined endpoint of new ischemic stroke (fatal or not), new MI (fatal or not), and other vascular death.
  • Acute Coronary Syndrome
    For patients with acute coronary syndrome (unstable angina / non-Q-wave MI), including patients who are to be managed medically and those who are to be managed with percutaneous coronary intervention (with or without stent) or CABG, Thrombonil has been shown to decrease the rate of a combined endpoint of cardiovascular death, MI, or stroke as well as the rate of a combined endpoint of cardiovascular death, MI, stroke, or refractory ischemia.

How Thrombonil Tablet Works?

Thrombonil is an inhibitor of platelet aggregation. A variety of drugs that inhibit platelet function have been shown to decrease morbid events in people with established atherosclerotic cardiovascular disease as evidenced by stroke or transient ischemic attacks, myocardial infarction, or need for bypass or angioplasty. This indicates that platelets participate in the initiation and/or evolution of these events and that inhibiting them can reduce the event rate.

Administration of Thrombonil Tablets with meals doesn’t significantly modify the bioavailability of Thrombonil as assessed by the pharmacokinetics of the main circulating metabolite.

Recommended Dosage of Thrombonil Tablets

In cases of Recent MI, Recent Stroke, or Established Peripheral Arterial Disease, The recommended daily dose of Thrombonil is 75 mg once daily.

For Patients with acute coronary syndrome, Thrombonil should be initiated with a single 300 mg loading dose and then continued at 75 mg once daily.

When to avoid Thrombonil Tablets?

The use of Thrombonil is contraindicated for individuals with hypersensitivity to clopidogrel or any component of the product. Patients with Active pathological bleeding such as peptic ulcer or intracranial hemorrhage should also avoid Thrombonil.

Thrombonil Tablets should be used during pregnancy only if clearly needed.

Possible Side Effects of Thrombonil Tablets

The most common side effects of Thrombonil are nausea, vomiting, and diarrhea. The incidence of blood dyscrasias is lower with Thrombonil. Rare cases of thrombotic thrombocytopenic purpura have been associated with Thrombonil, these usually remit when the drug is stopped.

Side effects reported in clinical trials include;

  • Pruritus
  • Purpura
  • Diarrhea
  • Rash
  • Neutropenia (decrease in white blood cells) is about 0.1%

Do not take Thrombonil or any other prescription drug without asking a qualified healthcare professional.