• Progrel 75 Tablet Contains
    Clopidogrel 75mg

Progrel 75 mg Tablets

 

What is Progrel 75 Used For?

Progrel is indicated for the reduction of atherothrombotic events as follows:

  • Recent MI, Recent Stroke or Established Peripheral Arterial Disease
    For patients with a history of recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease, Progrel has been shown to reduce the rate of a combined endpoint of new ischemic stroke (fatal or not), new MI (fatal or not), and other vascular death.
  • Acute Coronary Syndrome
    For patients with acute coronary syndrome (unstable angina / non-Q-wave MI), including patients who are to be managed medically and those who are to be managed with percutaneous coronary intervention (with or without stent) or CABG, Progrel has been shown to decrease the rate of a combined endpoint of cardiovascular death, MI, or stroke as well as the rate of a combined endpoint of cardiovascular death, MI, stroke, or refractory ischemia.

How Progrel Tablet Works?

Progrel is an inhibitor of platelet aggregation. A variety of drugs that inhibit platelet function have been shown to decrease morbid events in people with established atherosclerotic cardiovascular disease as evidenced by stroke or transient ischemic attacks, myocardial infarction, or need for bypass or angioplasty. This indicates that platelets participate in the initiation and/or evolution of these events and that inhibiting them can reduce the event rate.

Administration of Progrel Tablets with meals doesn’t significantly modify the bioavailability of Progrel as assessed by the pharmacokinetics of the main circulating metabolite.

Recommended Dosage of Progrel Tablets

In cases of Recent MI, Recent Stroke, or Established Peripheral Arterial Disease, The recommended daily dose of Progrel is 75 mg once daily.

For Patients with acute coronary syndrome, Progrel should be initiated with a single 300 mg loading dose and then continued at 75 mg once daily.

When to avoid Progrel Tablets?

The use of Progrel is contraindicated for individuals with hypersensitivity to clopidogrel or any component of the product. Patients with Active pathological bleeding such as peptic ulcer or intracranial hemorrhage should also avoid Progrel.

Progrel Tablets should be used during pregnancy only if clearly needed.

Possible Side Effects of Progrel Tablets

The most common side effects of Progrel are nausea, vomiting, and diarrhea. The incidence of blood dyscrasias is lower with Progrel. Rare cases of thrombotic thrombocytopenic purpura have been associated with Progrel, these usually remit when the drug is stopped.

Side effects reported in clinical trials include;

  • Pruritus
  • Purpura
  • Diarrhea
  • Rash
  • Neutropenia (decrease in white blood cells) is about 0.1%

Do not take Progrel or any other prescription drug without asking a qualified healthcare professional.